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Data · study · 2026

Analysis of gene expression in irradiated intratumoral mouse T cells

Listed in NCBI GEO

We aimed to identify promoters activated by ionizing radiation (IR) specifically in T cells by analyzing gene expression in intratumoral mouse T cells after in vivo IR treatment .

Description

Whole-body irradiation (WBI) was used instead of local IR to avoid contamination by non-irradiated T cells newly infiltrating from the periphery. MC38 tumor-bearing B6 mice received 1 or 5 Gy WBI, and differential gene expression was analyzed in FACS-sorted T cells from tumors at 1 h, 6 h, or 24 h post-irradiation, vs. T cells sorted from non-irradiated tumors.

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Life Sciences
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Genetics 70%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30517514 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3105enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (70%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title