Omics · study · 2026
Transcriptomic profiling of GOLM1 silenced A549 lung adenocarcinoma cells
Listed in NCBI GEO
GOLM1 is a Golgi-resident protein implicated in multiple cancers, but its role in lung adenocarcinoma remains incompletely understood.
Description
RNA sequencing was performed on A549 lung adenocarcinoma cells following siRNA-mediated silencing of GOLM1 using two independent siRNAs and a non-targeting control. Differential gene expression analysis was conducted to identify molecular pathways regulated by GOLM1 depletion, including alterations in cell cycle regulation, DNA replication, lysosomal pathways, and mitochondrial-associated processes.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337173 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337173 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1483734 ncbi.nlm.nih.gov/bioproject/PRJNA1483734 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE337173 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |