Excel · study · 2026
Effects of GFO® supplementation on cecal microbiota composition during prolonged fasting in rats
Listed in NCBI GEO
Prolonged fasting is known to alter gut microbiota composition and impair intestinal homeostasis.
Description
To investigate the effects of nutritional supplementation on fasting-associated microbiota changes, male Sprague-Dawley rats were administered GFO® (a nutritional formulation containing glutamine, dietary fiber, and oligosaccharides) or 15% glucose solution twice daily for 9 days. Animals underwent fasting from days 6 to 9.
A fed control group and a fasting-only group were included for comparison. Cecal contents were collected after euthanasia and subjected to 16S rDNA amplicon sequencing. This dataset was generated to evaluate fasting-associated alterations in gut microbial communities and the modulatory effects of GFO supplementation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334390 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334390 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1474918 ncbi.nlm.nih.gov/bioproject/PRJNA1474918 ↗
project · from NCBI GEO
Topics
- Stated by source
- Other
- From keywords
- Life Sciences
- Inferred from text
- Food sciences 69% · Sequencing 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE334390 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3006 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (69%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |