Excel · study · 2026
Gene expression data from human amniotic epithelial stem cell (hAESCs) treated with 20 uM Cinnamoylquinc Acid Derivatives
Listed in NCBI GEO
Gene expression profiling reveals structure-activity relationships of cinnamoylquinic acid derivatives in a stem-based tool.
Description
Cinnamoylquinic acids are bioactive polyphenolic compounds with many beneficial effects. Utilizing human amniotic epithelial stem cells (hAESCs), transcriptomic analysis was conducted to study the physiological effects of ten derivatives.
The ten compounds include: Tricaffeoylquinic acid, Tetraferuloylquinic acid, Tricoumaroylquinic acid, Tri(dimethoxycinnamoyl)quinic acid, Tetracaffeoylquinic acid, Triferuloylquinic acid, Methyl Tri(dimethoxycinnamoyl)quinate, Methyl tetracaffeoylquinate, Methyl tetraferuloylquinate, and Methyl tricaffeoylquinate. From gene expression data, additionalk analysis pinpointed the structure-functionality relationship based on moiety variations while hinting to possible structural improvments for bioactivity and druggability.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE280nnn/GSE280265 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280265 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1177477 ncbi.nlm.nih.gov/bioproject/PRJNA1177477 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE280265 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |