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Omics · study · 2026

Transcriptomic profiling of HT29 colorectal cancer cells treated with indole-3-pyruvic acid

Listed in NCBI GEO

Indole-3-pyruvic acid (IPyA) was investigated for its effects on gene expression in HT29 human colorectal adenocarcinoma cells.

Description

HT29 control and IPyA-treated cells were analyzed after 72 h using four biological replicates per group. Bulk RNA sequencing was performed using paired-end 150-bp reads on an Illumina NovaSeq 6000 platform.

The dataset was generated to characterize IPyA-induced transcriptional changes and support pathway-level analyses of the molecular response to IPyA.

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From keywords
Life Sciences
Inferred from text
Cancer 75% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34719414 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title