Data · collection · 2015
In vitro investigation of Brazilian Cerrado plant extract activity against Plasmodium falciparum , Trypanosoma cruzi and T. brucei gambiense
Listed in DataCite
The threatened Brazilian Cerrado biome is an important biodiversity hotspot but still few explored that constitutes a potential reservoir of molecules to treat infectious diseases.
Description
We selected eight Cerrado plant species for screening against the erythrocytic stages of Plasmodium falciparum , human intracellular stages of Trypanosoma cruzi and bloodstream forms of T. brucei gambiense , and for their cytotoxicity upon the rat L6-myoblast cell line.
Bioassays were performed with 37 hexane, ethyl acetate and ethanol extracts prepared from different plant organs. Activities against parasites were observed for 24 extracts: 9 with anti- P. falciparum , 4 with anti- T. cruzi and 11 with anti- T. brucei gambiense activities. High anti-protozoal activity (IC 50 values Connarus suberosus, Blepharocalyx salicifolius , Psidium laruotteanum and Myrsine guianensis .
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Overall, studies of plant extracts will contribute to increase the biodiversity knowledge essential for Cerrado conservation and sustainable development.
Links
Where it is published
- Repository landing page figshare.com/collections/_i_In_vitro_i_investigation_of_Brazilian_Cerrado_p… ↗
landing page · from DataCite
- Repository landing page figshare.com/collections/_i_In_vitro_i_investigation_of_Brazilian_Cerrado_p… ↗
landing page · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2092109 ↗
DOI / persistent id · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2092109.v1 ↗
DOI / persistent id · from DataCite
Documentation and papers
- CC-BY creativecommons.org/licenses/by/3.0/us ↗
license · from DataCite
- IsSupplementTo 10.1080/14786419.2015.1055264 doi.org/10.1080/14786419.2015.1055264 ↗
publication · from DataCite
Catalogue records · 4
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2092109.v1 ↗
metadata API · from DataCite
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2092109 ↗
metadata API · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2092109 ↗
catalogue entry · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2092109.v1 ↗
catalogue entry · from DataCite
Topics
- Stated by source
- Biological sciences · Biological sciences · Earth and related environmental sciences · Earth and related environmental sciences · Physical sciences · Physical sciences
- From keywords
- Ecology · Medicine & Health · Medicine & Health · Microbiology · Plant biology
Provenance · 2 source records, 15 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.6084/m9.figshare.c.2092109 | 14 d ago | JSON v1 |
| DataCite | 10.6084/m9.figshare.c.2092109.v1 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:earth-and-related-environmental-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:earth-and-related-environmental-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:physical-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:physical-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Medicine'] |
| concepts[field].local:field:medicine-health | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Medicine'] |
| created_date | source · DataCite | connector:datacite@1.0.0 | |
| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
| license | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| publication_date | source · DataCite | connector:datacite@1.0.0 | /data/attributes/dates |
| title | source · DataCite | connector:datacite@1.0.0 | /data/attributes/titles/0/title |
| updated_date | source · DataCite | connector:datacite@1.0.0 |