Data · study · 2026
Gene expression profiling of Venetoclax-treated HL-60 cells
Listed in NCBI GEO
Venetoclax is a selective BCL-2 inhibitor with antileukemic activity.
Description
To investigate the transcriptional alterations induced by Venetoclax in human acute myeloid leukemia cells, HL-60 cells were treated with Venetoclax for 48 h and subjected to whole-transcriptome expression profiling using the GeneChip PrimeView Human Gene Expression Array. HL-60 cells were treated with 9.788 μM Venetoclax for 48 h.
HL-60 cells without Venetoclax treatment were used as controls. Total RNA was isolated from control and Venetoclax-treated cells, and biotin-labeled cRNA was prepared and hybridized to PrimeView Human Gene Expression Array chips.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344362 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344362 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1515305 ncbi.nlm.nih.gov/bioproject/PRJNA1515305 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE344362 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |