Excel · study · 2026
Bulk RNAseq analysis of wildtype and Pim1-/- macrophages
Listed in NCBI GEO
PIM1 is a serine/threonine kinase that modulates immune responses and cellular metabolism.
Description
To examine the function of PIM1 in macrophage gene expression, peritoneal macrophages were isolated from wild-type and Pim1-/- mice. They were treated with 20 μg/mL oxidized low-density lipoprotein for 8 hours.
Total RNA was extracted and analyzed using bulk RNA sequencing to compare gene expression profiles and identify differentially regulated pathways between wild-type and Pim1-/- macrophages.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335106 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335106 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1477407 ncbi.nlm.nih.gov/bioproject/PRJNA1477407 ↗
project · from NCBI GEO
- PubMed 42558044 pubmed.ncbi.nlm.nih.gov/42558044 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE335106 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |