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Omics · study · 2026

Small RNA sequencing of small extracellular vesicles derived from human skeletal muscle cells during myogenic differentiation

Listed in NCBI GEO

Small extracellular vesicles (sEVs) derived from human skeletal muscle cells (HSkMCs) at different stages of myogenic differentiation were subjected to small RNA sequencing to characterize changes in sEV-associated miRNA profiles.

Description

Comparative analysis identified differentially expressed miRNAs during myogenic differentiation, including miR-193b-3p, which was enriched in sEVs derived from differentiated HSkMCs. These data were used to investigate differentiation-associated changes in sEV miRNA cargo and to identify candidate miRNAs involved in myogenesis.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE3476858 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:non-coding-rna-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title