Omics · study · 2026
RNA-seq analysis of dorsal root ganglia (DRG) from MIA-induced osteoarthritis mice with acupuncture or no treatment: Focus on neuro-immune crosstalk genes
Listed in NCBI GEO
Osteoarthritis (OA) is a chronic musculoskeletal disorder characterized by mechanical allodynia and dorsal root ganglion (DRG) neuroinflammation.
Description
Acupuncture at ST36 alleviates OA pain, but its effect on DRG transcriptional profiles remains unclear. This study aimed to identify key genes/pathways involved in acupuncture-mediated DRG neuro-immune remodeling using RNA sequencing.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE327nnn/GSE327205 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327205 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1449961 ncbi.nlm.nih.gov/bioproject/PRJNA1449961 ↗
project · from NCBI GEO
- PubMed 42598481 pubmed.ncbi.nlm.nih.gov/42598481 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE327205 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |