Data · dataset · 2026
Formulation strategies for modifying drug release from preformed solid implants
Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.17034/32641875.v1
Long-acting implantable drug delivery devices offer a means to overcoming current challenges within pharmacy such as pill fatigue, poor adherence to medication, low oral bioavailability, and dose-limiting side effects.
Description
Controlling drug release from such devices, however, remains a central challenge to their clinical translation. Accordingly, this thesis presents strategies to modulate and predict drug release from biodegradable solid implants. <br><br>Three model compounds were used throughout this thesis, carvedilol (CAR), amitriptyline hydrochloride (AMT), and risperidone (RIS).
An analytical method was developed and validated for each compound according to the International Council for Harmonisation (ICH) guideline Q2 R2. <br><br>Subsequently, three experimental chapters were developed outlining various methods of drug release modifications to solid-formed implantable devices.<br><br><i>Thesis is embargoed until 31 December 2030.</i>
Links
Where it is published
- DOI doi.org/10.17034/32641875.v1 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
- From keywords
- Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science · Medicine & Health · Medicine & Health · Medicine & Health
- Inferred from text
- Pharmacology and pharmaceutical sciences 74%
Provenance · 3 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/32641875 | 13 d ago | JSON v1 |
| Deakin Research Online | oai:figshare.com:article/32641875 | 13 d ago | JSON v1 |
| DMU Figshare | oai:figshare.com:article/32641875 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].anzsrc:group:3214 | enrichment · zivahub uct ac za | taxonomy-embedding@1.1.0 | title+keywords+description (74%) |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license_text | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |