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Omics · study · 2026

Transcriptomic profiling of PTD031-treated THP-1 cells

Listed in NCBI GEO

THP-1 cells were treated with PTD031 or vehicle control for 4 h and subjected to bulk RNA sequencing to characterize early transcriptional responses to PTD031.

Description

Differential expression and pathway enrichment analyses were performed to identify stress-response programs associated with PTD031 treatment, including redox-stress-related and ER stress-associated pathways.

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Expression profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
Biochemistry and cell biology 69% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32551115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3101enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (69%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title