Data · study · 2026
SBNO1 knockdown in the liver cancer cell lines HLF
Listed in NCBI GEO
Aberrant Notch signaling has been identified as a possible catalyst for hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) development.
Description
Genetic studies in Drosophila observed that the knockout of strawberry notch (sno) mimics loss of notch. Here, we elucidated the role of the mammalian Strawberry Notch 1 (SBNO1) in HCC and CCA development.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE277nnn/GSE277244 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE277244 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1161422 ncbi.nlm.nih.gov/bioproject/PRJNA1161422 ↗
project · from NCBI GEO
- PubMed 41649174 pubmed.ncbi.nlm.nih.gov/41649174 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE277244 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |