Omics · study · 2026
Transcriptomic profiling of rat brain tissue 21 days after middle cerebral artery occlusion
Listed in NCBI GEO
Ischemic stroke induces persistent molecular alterations in brain tissue during the recovery phase.
Description
To characterize transcriptomic changes at a late post-stroke time point, RNA sequencing was performed on hemisphere samples from adult rats subjected to sham surgery (n = 2) or middle cerebral artery occlusion (MCAO; n = 4). All tissues were collected 21 days after surgery.
This dataset was designed to compare the transcriptomic profiles of sham-operated and MCAO rats and contains no samples receiving cell transplantation, pharmacological treatment, or other therapeutic intervention.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345807 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345807 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1521999 ncbi.nlm.nih.gov/bioproject/PRJNA1521999 ↗
project · from NCBI GEO
- PubMed 42706574 pubmed.ncbi.nlm.nih.gov/42706574 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE345807 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |