small-RNA-seq of nine primary human cell types exposed in vitro to methylprednisolone

In addition, the current understanding of glucocorticoid effects on transcription in human cells is based primarily on studies of cancer cell lines, immortalized cell lines, or highly mixed populations of primary cells.

To advance the understanding of the effects of glucocorticoids on micro-RNA transcript abundance, we performed high-throughput sequencing of small RNAs (small-RNA-seq) on nine human primary cell types at two time points after in vitro exposure to the GC methylprednisolone.