Omics · study · 2026
Pulsed photobiomodulation reprograms the tumor immune microenvironment to restore local T cell–mediated antitumor immunity
Listed in NCBI GEO
We have employed a single cell sequencing approach using 10X Genomics scRNA-seq to study MC38 tumor infiltrated immune cell under Photobiomodulation(PBM) treatment.
Description
PBM, also termed low-level laser therapy (LLLT), is a non-invasive, drug-free physical modality that uses defined light wavelengths to modulate cellular functions. This study represents the first transcriptomic analysis of how PBM reshapes the tumor microenvironment and inhibits MC38 tumor growth.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318313 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318313 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1418572 ncbi.nlm.nih.gov/bioproject/PRJNA1418572 ↗
project · from NCBI GEO
- PubMed 42109854 pubmed.ncbi.nlm.nih.gov/42109854 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65% · Sequencing 75% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE318313 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |