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Data · study · 2026

Expression data from Txnrd2 deficient mouse gastrocnemius muscle

Listed in NCBI GEO

TXNRD2, encoded by Txnrd2, is a mitochondrial enzyme of the pyridine nucleotide–disulfide oxidoreductase family and a key component of the thioredoxin system, essential for maintaining redox homeostasis.

Description

Because skeletal muscle is highly metabolically active and depends on efficient mitochondrial function and redox balance to sustain energy production, we aimed to investigate the role of Txnrd2 in skeletal muscle. The Clariom S Mouse microarray from Affymetrix was used to investigate the dysregulation of gene expression in the gastrocnemius muscle of mice with a muscle-specific deletion of Txnrd2.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31052115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title