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Omics · study · 2026

Gene expression profile at single cell level of breast cell lines HMLE and BT-549

Listed in NCBI GEO

We explored cell heterogeneity by single cell RNA sequencing in normal (HMLE) and cancer (BT-549) mammary cell lines.

Description

HMLE is a non-transformed epithelial cell line that possesses only a very small subpopulation of CD44highCD24low cells with mesenchymal and stem-like properties. Given the rarity of the CD44highCD24low subpopulation (1%), we performed single-cell analysis either on the bulk population or on FACS-sorted CD44highCD24low enriched samples.

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From keywords
Life Sciences
Inferred from text
Cancer 75% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE23772615 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title