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Omics · study · 2026

CB1 receptor inhibition restores synaptoneurosomal alternative splicing landscape in fragile X syndrome mice

Listed in NCBI GEO

Using RNA sequencing, we performed gene expression profile of hippocampal synaptoneurosomes and bulk hippocampus from the same three animals.

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To evaluate synaptic content in hippocampal synaptoneurosomes compared to bulk hippocampus, we analyzed gene expression and described an enrichment of synaptic genes that makes synaptoneurosomal preparations suitable for the study of synaptic content.

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Life Sciences
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RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE28462715 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title