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Omics · study · 2026

Single-cell RNA and TCR sequencing of CD45+ immune cells from nephrectomized kidney allografts and matched peripheral blood

Listed in NCBI GEO

T cells are central mediators of transplant rejection, yet the differentiation pathways that sustain their pathogenic activity remain poorly defined.

Description

To address this, CD45+ immune cells from nephrectomized kidney allografts and matched peripheral blood mononuclear cells (PBMCs) were sorted and profiled using integrated single-cell RNA and T cell receptor sequencing (scRNA/TCR-seq).

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Expression profiling by high throughput sequencing · Homo sapiens · Other
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Life Sciences
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Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31900715 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title