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Excel · study · 2026

Liver transcriptome profiling of GAN-fed wild-type and hepatocyte-specific Hsf1-knockout mice

Listed in NCBI GEO

Heat shock factor 1 (HSF1) regulates cellular stress responses.

Description

This study used liver RNA sequencing to examine transcriptional changes associated with hepatocyte-specific Hsf1 deletion in a dietary model of metabolic dysfunction-associated steatohepatitis. Liver samples from wild-type and hepatocyte-specific Hsf1-knockout mice were compared after 28 weeks of Gubra Amylin NASH diet feeding.

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Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34753515 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title