Omics · study · 2026
Single-nucleus RNA-seq of gonadotropin-releasing hormone 3 (GnRH3) neurons in 7 day-post-fertilization (dpf) Tg(gnrh3:EGFP) zebrafish
Listed in NCBI GEO
We applied a single-nucleus RNA sequencing approach using 10x Genomics snRNA-seq to examine the developmental heterogeneity of GnRH3 neurons in 7 dpf zebrafish.
Description
GnRH3 serves as the key hypophysiotropic regulator of reproduction, yet the heterogeneity within its migratory neuronal population has remained unclear in 7 dpf zebrafish. By profiling nuclei from 7 dpf Tg(gnrh3:EGFP) larvae, this study provides the first single-cell-transcriptomic characterization of migrating GnRH3 neurons in 7 dpf zebrafish and offers new insights into their developmental organization and functional specialization.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE309nnn/GSE309816 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309816 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1363761 ncbi.nlm.nih.gov/bioproject/PRJNA1363761 ↗
project · from NCBI GEO
- PubMed 42415515 pubmed.ncbi.nlm.nih.gov/42415515 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Danio rerio · Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE309816 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:7955 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |