Omics · study · 2026
Xing-Pi-Qing-Gan decoction alleviates alcoholic liver disease through multi-omics and experimental verification of DDIT3-Nrf2/HO-1-mediated antioxidant defense
Listed in NCBI GEO
This study aimed to investigate the transcriptome changes of alcoholic liver disease treated with NIAAA model after administration of Xing-Pi-Qing-Gan decoction.
Description
The mice were divided into two groups: one group of NIAAA model mice, and the other group was administered simultaneously on the basis of modeling. After the experiment, total RNA was extracted from fresh liver for high-throughput RNA sequencing (RNA-seq), and the effect of Xing-Pi-Qing-Gan decoction on alcoholic liver disease and related host transcriptional changes were identified by differential gene expression analysis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310439 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310439 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1366297 ncbi.nlm.nih.gov/bioproject/PRJNA1366297 ↗
project · from NCBI GEO
- PubMed 41809881 pubmed.ncbi.nlm.nih.gov/41809881 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Disease 75% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE310439 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |