← Search

Omics · study · 2026

Single-Cell RNA Sequencing Analysis of Mouse Corneal Transplantation Models Under Tacrolimus and Rapamycin Treatment

Listed in NCBI GEO

In this study, we utilized single-cell RNA sequencing (scRNA-seq) to investigate the effects of tacrolimus and rapamycin on corneal graft survival following penetrating keratoplasty in mice.

Description

Post-transplantation, the recipient mice were administered daily intraperitoneal injections of tacrolimus, rapamycin, or PBS. Fifteen days after treatment, scRNA-seq was employed to detect molecular and cellular changes within the corneal tissues.

Links

Get the data

Where it is published

Documentation and papers

Topics

Stated by source
Expression profiling by high throughput sequencing · Mus musculus
From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE27524915 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:single-cell-rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title