Data · dataset · 2017
Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria
Listed in LSHTM Data Compass
Description
This dataset consists of two files: (1) a spreadsheet containing Isolates metadata that covers study site, age, sex, treatment status (study case), HIV status, MDR & pre-XDR status, as well as lineage information inferred from kvarq, phyressse (Phy) and TBProfiler (tbp); and (2) a spreadsheet that contains phenotypic resistance profiles to first line drugs (rifampicin, isoniazid, streptomycin and ethambutol) for all isolates and to second line drugs (capreomycin, fluoroquinolone, ethionamide and amikacin) for MDR isolates.
Table also lists presence of known resistance mutations as detected by the three resistance prediction tools kvarq, phyrese and tbprofiler.
Links
Where it is published
- DOI doi.org/10.1371/journal.pone.0184510.s001 ↗
DOI / persistent id · from lshtm ac uk
Catalogue records · 1
- OAI-PMH record datacompass.lshtm.ac.uk/cgi/oai2?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3… ↗
metadata API · from lshtm ac uk
Topics
- From keywords
- Earth & Environmental Science · Humanities · Life Sciences · Medicine & Health · Social Science
- Inferred from text
- Genome sequencing 65% · Sequencing 75% · Tabular 65%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| LSHTM Data Compass | oai:datacompass.lshtm.ac.uk:4456 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].local:field:earth-environmental | mapping · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | |
| concepts[modality].local:modality:genome-sequencing | enrichment · lshtm ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · lshtm ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:tabular | enrichment · lshtm ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | /metadata/dc/description |
| publication_date | source · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | |
| title | source · lshtm ac uk | connector:lshtm_ac_uk@1.0.0 | /metadata/dc/title |