Omics · study · 2026
Evolutionary transcriptomic and cellular specializations within the mammalian striatum
Listed in NCBI GEO
Description
In this study we generated and analyzed single-nucleus RNA sequencing (snRNA-seq) of human, chimpanzee, rhesus macaque (this study and GSE167920), marmoset (GSE151761 and GSE165578), bat caudate (CN) and putamen (Pu) separately, ferret caudate (GSE151761), and mouse caudoputamen (C-Pu)(GSE151761) spanning 94 million years of evolution. We identified novel interneuron cell types in bat Pu while uncovering fundamental cellular compositional and transcriptomic differences between primate and non-primate striata.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293075 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293075 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1242755 ncbi.nlm.nih.gov/bioproject/PRJNA1242755 ↗
project · from NCBI GEO
- PubMed 42185272 pubmed.ncbi.nlm.nih.gov/42185272 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens · Macaca mulatta
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE293075 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9544 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |