Data · study · 2026
Senescence Markers and Associated Transcriptomic Changes Expressed at Early Stages of Alzheimer’s Disease Neuropathological Change but Are Not Independently Related to Dementia Status
Listed in NCBI GEO
Cellular senescence is an important ageing mechanism that may affect the post-mitotic cells of the brain.
Description
We have examined a panel of senescence markers in human autopsy brain samples and investigated how senescence marker expression changes with the progression of Alzheimer’s disease neuropathological change (ADNC) and their relationship to dementia.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310124 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310124 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1365168 ncbi.nlm.nih.gov/bioproject/PRJNA1365168 ↗
project · from NCBI GEO
- PubMed 42589618 pubmed.ncbi.nlm.nih.gov/42589618 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE310124 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |