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Excel · study · 2026

Dexmedetomidine Mitigates Pulmonary Ischemia-Reperfusion Injury by Targeting Ferroptosis through β-catenin/TCF4 Pathway Activation

Listed in NCBI GEO

RNA sequencing was performed to characterize transcriptomic changes associated with dexmedetomidine treatment in MLE-12 mouse lung epithelial cells subjected to hypoxia/reoxygenation.

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Differential expression and functional enrichment analyses were used to identify genes and pathways potentially involved in the protective and anti-ferroptotic effects of dexmedetomidine.

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33919915 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title