Data · collection · 2015
A new azaphilone from the entomopathogenic fungus Hypocrella sp.
Listed in DataCite
This report describes the isolation of a new azaphilone, designated hypocrellone A ( 2 ), together with five known compounds ( 1 , 3 – 6 ) from a submerged culture of the entomopathogenic fungus Hypocrella sp.
Description
(isolate WYTY-21). The absolute stereostructures of the two compounds ( 1 and 2 ) were elucidated based on 1D and 2D NMR spectroscopic and mass spectrometric data combined with the data from various chemical transformations.
Hypocrellone A ( 2 ) and three ( 3 – 6 ) of the five known compounds were cytotoxic to hepatoma cells (cell line BEL-7404); IC 50 values ranged from 6.2 to 17.4 μM. At 200 μM, none of the six compounds was toxic to normal human liver cells (cell line HL-7702) or to normal human kidney epithelial cells (cell line HEK-293T).
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Where it is published
- Repository landing page tandf.figshare.com/collections/A_new_azaphilone_from_the_entomopathogenic_fungus_… ↗
landing page · from DataCite
- Repository landing page tandf.figshare.com/collections/A_new_azaphilone_from_the_entomopathogenic_fungus_… ↗
landing page · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2047307 ↗
DOI / persistent id · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2047307.v1 ↗
DOI / persistent id · from DataCite
Documentation and papers
Catalogue records · 4
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2047307.v1 ↗
metadata API · from DataCite
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2047307 ↗
metadata API · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2047307.v1 ↗
catalogue entry · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2047307 ↗
catalogue entry · from DataCite
Topics
- Stated by source
- Biological sciences · Biological sciences · Clinical medicine · Clinical medicine
Provenance · 2 source records, 13 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.6084/m9.figshare.c.2047307 | 15 d ago | JSON v1 |
| DataCite | 10.6084/m9.figshare.c.2047307.v1 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| concepts[disease].local:disease:cancer | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[disease].local:disease:cancer | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:clinical-medicine | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:clinical-medicine | source · DataCite | connector:datacite@1.0.0 | |
| created_date | source · DataCite | connector:datacite@1.0.0 | |
| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
| license | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| publication_date | source · DataCite | connector:datacite@1.0.0 | /data/attributes/dates |
| title | source · DataCite | connector:datacite@1.0.0 | /data/attributes/titles/0/title |
| updated_date | source · DataCite | connector:datacite@1.0.0 |