Excel · study · 2026
Integrated Transcriptomic and Proteomic Analysis of Gene Expression Changes in Brown Adipose Tissue During Cold Acclimatization in Rats
Listed in NCBI GEO
This study aims to conduct a combined analysis of differentially expressed genes in the transcriptome and proteome of brown adipose tissue from cold-tolerant rats, exploring potential biomarkers and therapeutic targets for cold adaptation.
Description
Male SD rats underwent intermittent cold exposure, with control animals maintained at room temperature. After 21 days, brown adipose tissue samples were collected following anaesthesia with 20% urethane.
High-throughput mRNA transcriptome sequencing identified differentially expressed genes within brown adipose tissue.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE311nnn/GSE311665 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE311665 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1368464 ncbi.nlm.nih.gov/bioproject/PRJNA1368464 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE311665 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |