Data · dataset · 2026
Experimental raw images and statistical data for the study "Pain sensitization stems from new insights into a unique type of memory: the joint conspiracy of neuronal organelles and the extracellular matrix"
Listed in ScienceDB
This dataset provides the raw experimental images and statistical source data supporting the study "Pain sensitization stems from new insights into a unique type of memory: the joint conspiracy of neuronal organelles and the extracellular matrix".
Description
Using a 49-day spared nerve injury (SNI) model in male Sprague-Dawley rats, the study examined structural and functional remodeling of dorsal hippocampal CA1 neurons and the perisynaptic extracellular matrix during persistent neuropathic pain.
The dataset includes: (i) original microscopy images - Nissl staining, immunohistochemistry (TLR9, IBA1, ACTN4, Integrin beta 1, N-cadherin), immunofluorescence (Fibronectin, GFAP), Golgi-Cox staining, and transmission electron microscopy of the hippocampal CA1 region; (ii) small RNA (miRNA) sequencing analysis plots, including volcano plot, heatmap and GO/KEGG enrichment analyses; and (iii) statistical data tables covering behavioral testing (von Frey paw withdrawal mechanical threshold over 49 days), quantitative image analysis and Sholl analysis.
Read the rest (1 more)
All original images are provided in TIFF format (137 image files, ~3.8 GB, plus 2 statistical tables and a README file). The data support the manuscript's conclusions regarding pain sensitization as a hippocampus-dependent, memory-related process.
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.013a1 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
- Inferred from text
- Image 75% · Microscopy 75% · Sequencing 75% · Zoology 69%
Provenance · 1 source records, 14 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.013a1 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].anzsrc:group:3109 | enrichment · scidb cn | taxonomy-embedding@1.0.0 | title+keywords+description (69%) |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[modality].local:modality:image | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:microscopy | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license_text | source · scidb cn | connector:scidb_cn@1.0.0 | |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |