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Excel · study · 2026

Effect of the depletion of YAP1 in adult spinal cord neural stem cells

Listed in NCBI GEO

Mouse spinal cord neural stem cells are know to be multipotent in vitro but mainly produce astrocytes in vivo.

Description

RNA sequencing and proteomic analysis showed that neural stem cells downregulate the Hippo/YAP1 pathway during OPC formation. To understand the implication of YAP1 in the oligodendrogliogenesis, we used transgenic cells expressing a truncated form of YAP1 and analyzed their mRNA expression in proliferation and differentiation

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE27411112 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title