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Table · study · 2026

Ribosome-associated RNA sequencing of medial prefrontal cortex parvalbumin interneurons following Foxo1 deletion

Listed in NCBI GEO

FOXO1 is required for maintaining cellular homeostasis in medial prefrontal cortex parvalbumin interneurons.

Description

To characterize the molecular consequences of FOXO1 loss, ribosome-associated transcripts were isolated specifically from parvalbumin interneurons in the medial prefrontal cortex of control and Foxo1 conditional knockout mice and profiled by RNA sequencing. Comparative transcriptomic analysis revealed alterations in autophagy-related transcriptional programs in Foxo1-deficient parvalbumin interneurons.

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Stated by source
Mus musculus · Other
From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34434413 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title