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Text · study · 2026

Transcriptomic Profiling of MCUB-Deficient Human Glioblastoma Cells

Listed in NCBI GEO

To examine the transcriptional effects of MCUB loss in human glioblastoma (GBM) cells, we compared gene expression profiles between MCUB-deficient cells and corresponding control cells.

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Cells were transduced with lentiviral constructs to establish stable MCUB deficiency, with scramble-transduced cells used as controls. Gene expression profiling was performed using the Agilent SurePrint G3 Human Gene Expression Microarray 8x60K.

The resulting data were used to identify changes in gene expression and associated biological pathways following MCUB loss.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31749714 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title