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PRMT6 suppresses intestinal inflammation by epigenetically repressing IL-1β [RNA-seq]

Listed in NCBI GEO

To investigate the effect of PRMT6 on the gene expression profile of macrophages under inflammatory conditions, wild-type (WT) and PRMT6-knockout (PRMT6-KO) bone marrow-derived macrophages (BMDMs) were stimulated with lipopolysaccharide (LPS), followed by transcriptome sequencing.

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Three biological replicates were included for each group.

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
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RNA sequencing 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34701215 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title