Excel · study · 2026
Transcriptome profiling of murine mesenchymal stem cells under bipotential osteogenic/adipogenic induction with STC2 treatment
Listed in NCBI GEO
This study aims to delineate the molecular mechanisms by which stanniocalcin 2 (STC2) regulates mesenchymal stem cell (MSC) lineage commitment.
Description
Murine MSCs were cultured under bipotential induction conditions (simultaneous osteogenic and adipogenic induction) and treated with either recombinant STC2 protein or vehicle control. Bulk RNA sequencing was performed to profile genome-wide gene expression changes, to identify differentially expressed genes and functional pathways underlying STC2-mediated shift of MSC fate toward osteogenesis and away from adipogenesis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338005 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338005 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1492087 ncbi.nlm.nih.gov/bioproject/PRJNA1492087 ↗
project · from NCBI GEO
- PubMed 42702890 pubmed.ncbi.nlm.nih.gov/42702890 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE338005 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |